Monensin ic50
Web1、Monensin 莫能霉素，CAS：22373-78-0. 简单描述：天然离子载体 (ionophore)，选择性结合单价阳离子如Li+、Na+、K+、Rb+、Ag+和Tl+，并将这些阳离子转运到细胞膜内 … WebMonensin A is a spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. It has a role as a coccidiostat, an antifungal agent and an …
Monensin ic50
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WebBrefeldin A (BFA) is a fungal macrocyclic lactone and a potent, reversible inhibitor of intracellular vesicle formation and protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus [1]. BFA and its … Web10 apr. 2024 · BCG generates limited long-lasting adaptive memory responses leading to short-lived protection against adult pulmonary tuberculosis (TB). Here we show…
WebPublished OnlineFirst September 4, 2013; DOI: 10.1158/1535-7163.MCT-13-0445 Molecular Cancer Therapeutics Small Molecule Therapeutics Gramicidin A Induces Metabolic Dysfunction and Energy Depletion Leading to Cell Death in Renal Cell Carcinoma Cells Justin M. David1,2, Tori A. Owens2, Sonali P. Barwe2, and Ayyappan K. Rajasekaran2 WebRVX-208 (BET bromodomain抑制剂) 5mg加入1.35ml DMSO，或者每3.7mg加入1ml DMSO，配制成10mM溶液。. SD1159-10mM用DMSO配制。. RVX-208是一种有效的BET bromodomain抑制剂，作用于BD2，无细胞试验中IC50为0.510μM，比作用于BD1选择性高170倍。. Phase 2。. 作为BET溴结构域蛋白抑制剂，RVX-208 ...
Web28 nov. 2024 · Request PDF Chemotherapeutic Potential of Monensin as an Anti-microbial Agent ... Monensin and nigericin showed IC50 values < 1 µM, whereas salinomycin was … Web90 g/ton monensin to assist in coccidiosis control. Analysis of a feed sample using the Minder calorimetric method re-vealed 658 g/ton monensin.2,3 The pigs had received an es-timated 34 mg monensin/kg body weight. Losses stopped soon after the feed was changed, but surviving pigs were gaunt for several weeks following the incident. The history and
Web莫能菌素Monensin 细胞内蛋白运输的抑制剂. 流式胞内染色中最常用的活化细胞方法就是用一定浓度的PMA和Ionomycin刺激细胞4-6小时，同时加入蛋白转运抑制剂（通常是monensin或brefeldin A）阻止高尔基体将新分泌蛋白运输到细胞外，从而达到通过流式来检测细胞因子的目的。
WebThe monovalent iono- phores efficiently killed both asexual parasites and gametocytes with a nanomolar 50% inhibitory concentration (IC50). Salino- mycin showed a fast speed of … how to view ruler in ms wordWebMonensin A is an ionophore related to the crown ethers with a preference to form complexes with monovalent cations such as: Li +, Na +, K +, Rb +, Ag +, and Tl +. [4] [5] Monensin A is able to transport these cations … how to view rubric in canvasWebFrom the comparison of the IC50 values, it appeared that monensin (IC50 16.77 303 ± 2.46) is about twice as active as salinomycin (IC50 34.88 ± 5.13). 304 To assess the … origami poinsettia flower instructionsWebAmong these drugs are monensin, nigericin, vincristine, vindesine, ethylhydrocupreine and salinomycin with in vitro IC50s at nanomolar concentrations (0.3, 0.4, 2, 6, 26 and 188 nM, respectively). Other compounds such as hycanthone, amsacrine, aphidicolin, bepridil, amiodarone, ranolazine and triclocarban showed in vitro IC50 values below 5 microM in … how to view rpt filesWebThree chimeric proteins were obtained by fusing together the dianthin gene and DNA fragments encoding for the following membrane-acting peptides: the N-terminus of … how to view rss feedsThe half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological component by 50%. The biological component could be an enzyme, cell, cell re… origami poinsettia flowersWebWe noted that monensin antagonized GSK3 inhibitors less efficient- ly than the signaling initiated by Wnt ... (OM-153). Compound 24 showed picomolar IC50 inhibition in a … origami poinsettia instructions